Enable discoveries and get to your next breakthrough moment faster! The BD FACSMelody™ offers high-end sorting in an easy-to-use package for any researcher. It has been contributing to the research in...
“The FACSMelody™ is very simple to use. We can train a user within an hour, even if they have limited flow cytometry experience”, says Dr. Andrea L. Holme, Senior Lecturer for Cytometry at the University of Western Australia,...
The human immune system fights not only external pathogens but also clears internal abnormalities like dying and cancer cells. The cancer immunity cycle begins when antigens produced by tumor cells are processed by dendritic cells for antigen presentation. This is followed by additional signals that activate and induce anti-tumor response by T cells, eventually resulting […]
B-cell diversity is generated by a highly regulated, multistep process. Abnormal B-cell development and function can lead to malignant transformation. Advances in the understanding of the regulatory process that control B-cell lymphopoiesis and function have enabled proper classification of B-cell neoplasms and the development of targeted therapies. The attached poster enables you to get an […]
BD Biosciences organized the first BD ever single-cell multi-omics user group meeting at BD headquarters, Winnersh in March 2019, in the UK. The aim of this event was to bring together users of the BD multi-omics technology and share their work & experience. An exciting day resulted with the speakers talking about how the BD […]
By Dr. Wendy Beguelin, Weil Cornell Medical College. A multiomics approach During humoral immune response or infections, subsets of B-cells migrate to germinal centres in lymphoid follicles located in the lymph nodes and the spleen. Some of these germinal centre B-cells (GC B-cells) differentiate into memory B-cells and plasma cells. Understanding the biology of GC […]
Evaluating the expression patterns of multiple inhibitory receptors Persistent antigen stimulation of T-cells, typically observed during chronic infections or in tumor microenvironments, results in the loss of antigen-specific CD8+ T-cell effector function. This phenomenon is referred to as T-cell exhaustion and is characterised by the progressive loss of function and proliferative capacity, eventually resulting in […]
The past two years have seen the “cell therapy revolution” begin It now sees the patient’s cells being modified to fight a disease. This revolution brings along unique challenges from discovery through clinical trials to the clinic. An evolving regulatory landscape, rapid advances in manufacturing technologies, products with complex mechanism of action and inherent variability […]
Discover a fully automated sample preparation solution The March of 2019 saw the release of a long-missing, fully automated sample preparation solution by BD. The BD FACSDuet™ sample prep system, when fully integrated with the BD FACSLyric™ flow cytometer, provides a complete walkaway sample to answer solution. Through its automation, the BD FACSDuet™ drives higher […]
BD Horizon Brilliant™ Ultraviolet dyes are being reformulated BD Horizon Brilliant™ Ultraviolet dyes are being reformulated with improved chemistry to allow you to better optimise your flow cytometry experiments. The new formulations have similar emission and excitation properties as before but have the additional advantage of reduced spillover into the BUV395 detector. BUV563, BUV737 and […]
The interactions between B cells and T cells within the germinal centres of peripheral lymphoid organs are crucial for the selection of high affinity B cells and development of long-lived memory cells in the context of T-cell dependent immune responses. Chemokine receptors play key roles in the homing, trafficking and retention of B cells and […]