CYTO OF THE EXTREME
A multiomics approach to defining the nature of early malignant transformations of the immune system - Webinar
Continue readingA multiomics approach to defining the nature of early malignant transformations of the immune system -Webinar
The CytohubBy Dr. Wendy Beguelin, Weil Cornell Medical College. During humoral immune response or infections, subsets of B-cells migrate to germinal centres in lymphoid follicles located in the lymph nodes and...
Continue readingEvaluating the expression patterns of multiple inhibitory receptors associated with T-cell exhaustion using multicolor flow cytometry
Scientific PublicationPersistent antigen stimulation of T-cells, typically observed during chronic infections or in tumor microenvironments, results in the loss of antigen-specific CD8+ T-cell effector function. This phenomenon is referred to as...
Continue readingStandardised flow cytometry, a key analytical platform in cell...
The CytohubThe past two years have seen the “cell therapy revolution” begin. It now sees the patient’s cells being modified to fight a disease. This revolution brings along unique challenges from discovery through clinical trials to the clinic. An...
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BD FACSDuet™- Experience the difference of a lab in rhythm
The CytohubDiscover a fully automated sample preparation solution The March of 2019 saw the release of a long-missing, fully automated sample preparation solution by BD. The BD FACSDuet™ sample prep system, when fully integrated with the BD FACSLyric™ flow cytometer, provides a complete walkaway sample to answer solution. Through its automation, the BD FACSDuet™ drives higher […]
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Reformulated for decreased spillover – The new BD Horizon Brilliant™ Ultraviolet dyes.
The CytohubBD Horizon Brilliant™ Ultraviolet dyes are being reformulated with improved chemistry to allow you to better optimise your flow cytometry experiments. The new formulations have similar emission and excitation properties as before but have the additional advantage of reduced spillover into the BUV395 detector. BUV563, BUV737 and BUV805 have already been reformulated, and BUV496 and […]
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Reagents to study B-cell and T-cell interactions
The CytohubThe interactions between B cells and T cells within the germinal centres of peripheral lymphoid organs are crucial for the selection of high affinity B cells and development of long-lived memory cells in the context of T-cell dependent immune responses. Chemokine receptors play key roles in the homing, trafficking and retention of B cells […]
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Patient well-being – The ultimate aim of all flow cytometry research
The CytohubAs flow cytometrists, our focus is mostly on setting up the instruments and designing experiments with the most appropriate reagent panels. However, an undeniable fact is that our overriding concern should be about the suffering patients, who badly need our expertise and continuous research. To shed light on this aspect, BD organised an event titled […]
Continue readingThe BD LSRFortessa™ X20 and BD FACSCelesta™ operator course at the BD European Training Centre– Feedback from participants
The CytohubAt the BD European Training Centre in Belgium, we offer a 4.5-day training course that teaches users how to work with the BD LSRFortessa™, BD LSRFortessa™ X-20, and BD FACSCelesta™. This exciting training program conducted by BD experts teaches users not only how to work with and maintain these machines, but also covers aspects of […]
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Isolation of Peripheral Blood Mononuclear Cells (PBMCs) made easy.
The CytohubThe efficient and quick isolation of lymphocytes (B-cells, T-cells, NK cells) and monocytes, both commonly called peripheral blood mononuclear cells or PBMCs, is extremely important for scientists and clinicians working in the field of immunology. Compared with the traditional ficoll-gradient method, BD Vacutainer™ CPT tubes offer great advantages by simplifying the process of PBMC isolation. […]
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BD™ AbSeq range of antibody-oligo conjugates
The CytohubWe are proud to announce the creation of the new block featuring the list of BD™ AbSeq antibody conjugates on www.flowcytometry-news.com. Unlike in conventional flow cytometry, BD™ AbSeq antibodies are conjugated not to dyes but to oligonucleotides. The BD™ AbSeq can be integrated with the BD Rhapsody™ system to enable an efficient workflow that allows researchers to […]
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The first publication featuring the BD Rhapsody™ system – Reliability of human cortical organoid generation
Scientific PublicationUse of BD Rhapsody™ system for whole transcriptome analysis We are proud to present the first results of a study published in Nature Methods, in which the BD Rhapsody™ system was used for whole transcriptome analysis. In this publication, transcriptional time course, immunocytochemistry and single-cell analyses are used to demonstrate that the derivation of hCS […]
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BD™ AbSeq assay is one of the Top 10 innovations of 2018
The CytohubThe BDTM AbSeq assay has been nominated by The Scientist© magazine One of the Top 10 Flowcytometry Innovations of 2018! The BDTM AbSeq assay enables immunology researchers to simultaneously understand RNA and protein expression across thousands of individual cells to further their understanding of the role genes and proteins play in biological systems. The assay […]
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