CYTO OF THE EXTREME
BD single-cell multi-omics user meeting seminar series Part 2: Evolution, challenges and the future of single-cell immunology – Christina Chang
Continue readingCLL phenotyping with BD Rhapsody™ Targeted Panels and BD® AbSeq assays
The CytohubChronic Lymphoid Leukemia (CLL), the most common form of leukemia in adults, is often characterised by progressive accumulation of incompetent lymphocytes in blood and bone marrow. Recent bulk RNA studies...
Continue readingBD single-cell multi-omics user meeting seminar series. Part 2 : Christina Chang, PhD
The CytohubPart 2: Evolution, challenges and the future of single-cell immunology – Christina Chang In this webinar, the second in the series of the BD Multi-Omics user day presentations, Christina Chang...
Continue readingBD single-cell multi-omics user meeting seminar series. Part 1...
The CytohubSimultaneous single-cell mRNA and epitope mapping of human CD4+ T-cells using the BD Rhapsody™ and the BD™ AbSeq platform “ Currently a senior post-doctoral fellow in John Todd’s lab at the University of Oxford, my primary research aims...
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Breakthrough with the BD FACSMelody™ Cell Sorter
The CytohubEnable discoveries and get to your next breakthrough moment faster! The BD FACSMelody™ offers high-end sorting in an easy-to-use package for any researcher. It has been contributing to the research in cutting-edge areas like stem cell research, multiomics, immunology and cancer research. Here, we present a list of publications in high-impact journals, citing the BD FACSMelody™. […]
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Creating the next generation of flow cytometry leaders -BD FACSMelody™ in action in Australia!
The Cytohub“The FACSMelody™ is very simple to use. We can train a user within an hour, even if they have limited flow cytometry experience”, says Dr. Andrea L. Holme, Senior Lecturer for Cytometry at the University of Western Australia, and a happy BD FACSMelody™ user. Watch the video to learn about the work being done by […]
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Flow cytometry in the study of anaerobic bacteria – The BIOASTER ANOXIC Platform
The CytohubThe various species of bacteria inhabiting human and animal bodies, particularly in the gut microbiota, play key roles in many biological processes. Important health issues like undernutrition, irritable bowel syndrome, metabolic disorders, skin diseases and many others are linked to gut bacteria and their functions. As bacteria in the gut are anaerobic and cannot be […]
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The role of immune checkpoint receptors in cancer immunity
The CytohubThe human immune system fights not only external pathogens but also clears internal abnormalities like dying and cancer cells. The cancer immunity cycle begins when antigens produced by tumor cells are processed by dendritic cells for antigen presentation. This is followed by additional signals that activate and induce anti-tumor response by T cells, eventually resulting […]
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Origin of normal and neoplastic B-cells
The CytohubB-cell diversity is generated by a highly regulated, multistep process. Abnormal B-cell development and function can lead to malignant transformation. Advances in the understanding of the regulatory process that control B-cell lymphopoiesis and function have enabled proper classification of B-cell neoplasms and the development of targeted therapies. The attached poster enables you to get an […]
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The first BD single-cell multi-omics user group meeting – Recap video
The CytohubBD Biosciences organized the first BD ever single-cell multi-omics user group meeting at BD headquarters, Winnersh in March 2019, in the UK. The aim of this event was to bring together users of the BD multi-omics technology and share their work & experience. An exciting day resulted with the speakers talking about how the BD […]
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Webinar: A multiomics approach to defining the nature of early malignant transformations of the immune system
The CytohubBy Dr. Wendy Beguelin, Weil Cornell Medical College. A multiomics approach During humoral immune response or infections, subsets of B-cells migrate to germinal centres in lymphoid follicles located in the lymph nodes and the spleen. Some of these germinal centre B-cells (GC B-cells) differentiate into memory B-cells and plasma cells. Understanding the biology of GC […]
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Evaluating the expression patterns of multiple inhibitory receptors associated with T-cell exhaustion using multicolor flow cytometry
Scientific PublicationEvaluating the expression patterns of multiple inhibitory receptors Persistent antigen stimulation of T-cells, typically observed during chronic infections or in tumor microenvironments, results in the loss of antigen-specific CD8+ T-cell effector function. This phenomenon is referred to as T-cell exhaustion and is characterised by the progressive loss of function and proliferative capacity, eventually resulting in […]
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Webinar: Standardised flow cytometry, a key analytical platform in cell therapy manufacturing
The CytohubThe past two years have seen the “cell therapy revolution” begin It now sees the patient’s cells being modified to fight a disease. This revolution brings along unique challenges from discovery through clinical trials to the clinic. An evolving regulatory landscape, rapid advances in manufacturing technologies, products with complex mechanism of action and inherent variability […]
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