Interview with Vesna Melkebeek, Ph.D. Tell us about your scientific background and your work. I have a Ph.D. in Veterinary Immunology and worked as a postdoc for several years before joining BD. During my academic career, I...
Data analysis is an extremely important part of a flow cytometry experiment. FlowJo™, the leading platform for superior analysis is a powerful tool that is helping scientists further their immunology...
Dendritic cells (DCs) play an important role in innate and acquired immunity. They are the antigen-presenting cells that prime naive T cells and elicit memory T cell responses to foreign antigens. DC subsets can be classified into three...
Do you run multicolour flow cytometry experiments with more than 10 colours? Do you use tools like Spillover Spread Matrix (SSM) to predict spread and design multicolour panels? Do you find discrepancies between predicted and measured spread, resulting in sub-optimal resolution? If the answer to these questions is yes, then this webinar is for you! […]
Regulatory T cells or Tregs are CD4 T cells that are essential for maintaining peripheral tolerance, preventing autoimmunity and limiting chronic inflammatory diseases. Naturally occurring Tregs were first characterized within the CD4+CD25+ T cell populations. Tregs express the transcription factor Foxp3, which is essential for their function. Over the years, specific Treg subsets have been […]
At BD Biosciences, we greatly value your research and your opinion. So, we have taken the feedback that we have received from you to create a brand-new digital experience. Our new BD Biosciences website will not only make your ordering experience more pleasant but will also help you find the tools and solutions you need […]
At the beginning of the new millennium, researchers had reached a plateau in the number of parameters that could be analysed in a flow cytometry experiment. This was due to the limited number of fluorochromes available and the overlaps that occurred in their excitation spectra with the available lasers. Then the Nobel Prize-winning discovery of […]
Addressing challenges in a new era of flow cytometry – A webinar by experts How, when, and why should isotype controls be included in flow cytometry experiments? What are some key strategies in flow cytometry panel design? Is spectral flow cytometry the future and will it replace traditional flow cytometry? Do you wish to get […]
The COVID-19 pandemic is an ongoing global challenge. It is a mild to moderate respiratory tract infection in most people but can cause life-threatening respiratory failure or persistent debilitating symptoms in a subset of patients.1 The mechanisms of protective immunity in mild cases and the pathogenesis of severe COVID-19 remain unclear. It has been proposed […]
In this application note, a study is presented that details a stepwise approach towards the intracellular staining and assessment of various immune cell types in a mouse model of obesity. Obesity can create an inflammatory environment that may lead to the production of exhausted T cell phenotypes. The loss of T cell effector function associated […]
Flow cytometry experiments can sometimes be challenging even for the most experienced scientists. Handy tips and tricks from experts are always useful and can provide answers during trying times in the laboratory. BD Biosciences, a leader in flow cytometry and immunology for the past 40 years, knows this all too well. We wish nothing more […]
Abstract: The composition of the immune infiltrate in the human tumor microenvironment is a critical determinant of disease progression. Immunotherapies to treat cancer have achieved remarkable successes, but an inherent weakness of current treatment approaches is that the targeted immune subsets are not exclusive to tumors. In an effort to identify tumor-unique immune features that […]