Henrick et al., Bifidobacteria-mediated immune system imprinting early in life, Cell (2021), https://doi.org/ 10.1016/j.cell.2021.05.030 There is mounting evidence to suggest that during the first 3 months of life, the infant...
Interview with Vesna Melkebeek, Ph.D. Tell us about your scientific background and your work. I have a Ph.D. in Veterinary Immunology and worked as a postdoc for several years before joining BD. During my academic career, I was mainly studying the impact of different vaccination strategies and immunomodulatory adjuvants on the intestinal mucosal immune system in animals using flow cytometry, cell...
Data analysis is an extremely important part of a flow cytometry experiment. FlowJo™, the leading platform for superior analysis is a powerful tool that is helping scientists further their immunology and immunophenotyping results. FlowJo™ users enjoy the support and assistance of a large group of expert BD application scientists. Want to know what BD’s FlowJo™ […]
Dendritic cells (DCs) play an important role in innate and acquired immunity. They are the antigen-presenting cells that prime naive T cells and elicit memory T cell responses to foreign antigens. DC subsets can be classified into three types. These are plasmacytoid DC (pDC), myeloid/conventional DC1 (cDC1) and myeloid/conventional DC2 (cDC2). This application note describes […]
Regulatory T cells or Tregs are CD4 T cells that are essential for maintaining peripheral tolerance, preventing autoimmunity and limiting chronic inflammatory diseases. Naturally occurring Tregs were first characterized within the CD4+CD25+ T cell populations. Tregs express the transcription factor Foxp3, which is essential for their function. Over the years, specific Treg subsets have been […]
At BD Biosciences, we greatly value your research and your opinion. So, we have taken the feedback that we have received from you to create a brand-new digital experience. Our new BD Biosciences website will not only make your ordering experience more pleasant but will also help you find the tools and solutions you need […]
At the beginning of the new millennium, researchers had reached a plateau in the number of parameters that could be analysed in a flow cytometry experiment. This was due to the limited number of fluorochromes available and the overlaps that occurred in their excitation spectra with the available lasers. Then the Nobel Prize-winning discovery of […]
In this application note, a study is presented that details a stepwise approach towards the intracellular staining and assessment of various immune cell types in a mouse model of obesity. Obesity can create an inflammatory environment that may lead to the production of exhausted T cell phenotypes. The loss of T cell effector function associated […]
What do you, the researcher, need the most today? How can you get to that big moment of discovery- that ‘ah-ha’ moment- that you spend so much time working for? Biology is a complex science. Today’s researchers require cutting-edge tools to dive deeper into elusive biological questions. Their need is for state-of-the-art technology to gain […]
Flow cytometry is serious science, but shouldn’t science be fun? Any scientist will tell you that the adventure of discovery and the thrill of experimentation make for a very exciting experience. We at BD Biosciences have always supported the playful side of science. So, we came up with a game that lets you choose your […]
The BD FACSymphony™ family of cell analysers has enabled the simultaneous detection of 30-50 parameters, thereby helping labs leverage and enhance the power of flow cytometry. BD FACSymphony™ analysers are highly customisable to meet your research priorities and can be configured to satisfy your needs, both present and future. This family of analysers has been […]