Identification of a novel arthritis-associated osteoclast precursor macrophage regulated by FoxM1
Scientific PublicationThe authors of this article (Hasegawa, et.al, Nat.Immun 2019) have studied the formation of osteoclasts, which play a crucial role in arthritic bone erosion. They have developed an original protocol...
Continue reading 2minProstaglandin E2 stimulates the expansion of regulatory haematopoetic stem and progenitor cells in Type 1 diabetes
Scientific PublicationThe transplant of Haematopoetic Stem and Progenitor cells (HSPC) has been employed in the treatment of haematological malignancies. However, studies have shown that HSPCs also possess immunoregulatory properties, making them...
Continue reading 2minEFIS On Tour with BD in the Czech Republic
The CytohubBD, a supporter of the EFIS On Tour program, was present at the event held recently at the Czech Academy of Sciences. This was the second EFIS On Tour supported by BD, following the event in Istanbul on...
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BD Horizon Brilliant™ Ultraviolet 615 Reagents – Expand your panel with BD Horizon™ BUV615
Non classéThe BD Horizon Brilliant™ Ultraviolet 615 (BUV615) is a tandem dye that is excited by the 355 nm laser and has an emission peak at 616 nm. The newest member of the BD Horizon Brilliant™ UV dyes family, BUV615, gives researchers greater flexibility in panel design using the UV laser. The BUV615 provides excellent resolution […]
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Fluorescence assisted cell-sorting in a oncohematology laboratory
The CytohubFACS or fluorescence assisted cell sorting, is an efficient technique to sort and select specific cell types from mixed populations. The authors of this poster have carried out molecular biology experiments like fluorescent in-situ hybridization (FISH), TCR re-arrangement and allele specific oligonucleotide tests on bone marrow samples taken from multiple myeloma, B-ALL, B-LS and mastocytosis […]
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BD OptiBuild™ – Obtaining the best results by titrating
The CytohubThe BD OptiBuild™ portfolio offers a wide range of dye-antibody combinations, allowing researchers to design sophisticated panels with minimum delay. However, once a panel is designed, the optimal concentration of the reagent for your specific sample needs to be established. To get the best results from a 50 µg reagent vial, a titration series of […]
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The BD Biosciences Cell Sorting & Multiomics roadshows
News & EventBD Biosciences is pleased to invite you to a roadshow showcasing its cell-sorting and multi-omics workflow, featuring the BD FACSMelody™ cell-sorter and the BD Rhapsody™ Single-Cell Analysis System. This workflow combines flow cytometry and single cell multi-omics analysis to gain new insights into cell heterogeneity that would not be possible using conventional phenotyping approaches. The […]
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BD Horizon™ Dri Chroma – The Brilliance of a complete panel in a tube
The CytohubBD Horizon™ Dri Chroma is a new technology that allows up to 16 reagents, including up to 5 BD Horizon™ Brilliant reagents, to be cocktailed and supplied in a dried down format in a single tube. This means greater workflow efficiency and stability versus liquid reagents. The BD Horizon™ Dri Chroma multicolour panels also show […]
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Simultaneous analysis of mRNA and proteins in mouse immune cells using the BD™ Mouse Single-cell multiplexing kit and the BD™ AbSeq assay on the BD Rhapsody™ system
The CytohubThe authors of this poster have studied the effects of obesity on immune cell populations in mice. They used cells isolated from epididymal fat, thymus, spleen and bone marrow from mice placed on high fat (HFD) and control diets. DNA-barcoded universal antibodies from the BD™ Mouse Single-cell Multiplexing kit allowed them to combine 8 samples […]
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Exploring tumor heterogeneity of chronic lymphocytic leukemia (CLL) using a unique workflow.
The CytohubCLL or chronic lymphocytic leukemia is the most common form of leukemia in adults. Understanding the heterogeneity of CLL tumor cells is important for the development of treatments and many bulk RNA-sequencing studies have provided insights into CLL pathogenesis. However, the complex mixture of cells used in such studies has failed to accurately elucidate the […]
Continue readingBD FACSMelody™ and BD Rhapsody™: Flow cytometry and Multi-Omics walking hand-in-hand down the aisle of single-cell analysis!
The CytohubAre you wishing for new insights into cell heterogeneity that phenotyping can’t reveal? What if you could combine flow cytometry and Multi-Omics in a smooth workflow to gain an unprecedented view into single cells? The combination of the BD FACSMelody™ cell sorter and the BD Rhapsody™ single-cell analysis system enables you to achieve just these. […]
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Whole transcriptome analysis (WTA) of a single cell – Now made easy.
The CytohubUnraveling the whole transcriptome of a single cell is now easier with the BD Rhapsody™ Whole Transcriptome Analysis (WTA) Amplification Kit. First, the lysis, capture of mRNAs using the bead-based retrieval mechanism of the BD Rhapsody™ and cDNA library preparation are carried out. Following this, the BD™ WTA Amplification Kit is used to generate whole […]
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