Immunophenotyping of human dendritic cell population

News & innovations

Dendritic cells (DCs) play an important role in innate and acquired immunity. They are the antigen-presenting cells that prime naive T cells and elicit memory T cell responses to foreign antigens.  DC subsets can be classified into three types. These are plasmacytoid DC (pDC), myeloid/conventional DC1 (cDC1) and myeloid/conventional DC2 (cDC2). This application note describes […]

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OMIP-068: High-dimensional characterization of global and antigen-specific B cells in chronic infection

Scientific Publication

OMIP-068: High-dimensional characterization In this OMIP (Optimised Multicolour Immunophenotyping Panel), the authors describe a 24-color panel to characterise antigen-specific B cells and for the precise delineation of B cell subsets in chronic infection.1 B cells play an important role in infection response through the production of antibodies, antigen presentation and secretion of cytokines. The antibodies […]

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OMIP-070: NKp46-based 27-color phenotyping to define natural killer cells isolated from human tumor tissues

Scientific Publication

Optimised Multicolour Immunophenotyping Panel In this OMIP (Optimised Multicolour Immunophenotyping Panel), the authors describe a 27-color phenotyping panel to study NK, or Natural Killer cells.1 The interest in NK cells began in the 1970s when it was discovered that they possess the ability to destroy tumor cells, and could play a role in controlling malignancies […]

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