Cell perturbation using the CRISPR technique Earlier on www.flowcytometry-news.com, we featured an article on the use of the BD Rhapsody™ system to perform highly scalable and more sensitive CRISPR screens. In cell perturbation using the CRISPR technique, single guide RNAs (sgRNAs) are used to guide the endonuclease Cas9 to create a targeted double-strand break, the […]
Webinar by Prof. Susan Schlenner, University of Leuven, Belgium Regulatory T cells (Tregs) are a subset of CD4+ T cells that possess immunosuppressive functions. They play a key role in human health as their malfunction results in allergies and auto-inflammatory disorders. Loss of regulatory T cells results in a rare autoimmune polyendocrine syndrome called IPEX, […]
The pathogenesis of B cell malignancies is a dynamic process The pathogenesis of B cell malignancies is a dynamic process involving reciprocal interactions between malignant cells and surrounding components in the tumour microenvironment. In the case of certain B cell lymphomas, neoplastic cells migrate to lymphoid sites and prompt the infiltration of non-malignant immune cells. […]
BD Biosciences is proud to present a series of educational videos, aptly titled ‘Scientist to Scientist Educational Series’, featuring insightful advice by BD scientists on how to get better and more impactful flow cytometry data by designing the correct panel. Click HERE to watch the videos and stay tuned for more videos in the coming months.