Delineation of functional Treg subsets using cell surface marker expression

News & innovations, Training and education

Regulatory T cells or Tregs are CD4 T cells that are essential for maintaining peripheral tolerance, preventing autoimmunity and limiting chronic inflammatory diseases. Naturally occurring Tregs were first characterized within the CD4+CD25+ T cell populations. Tregs express the transcription factor Foxp3, which is essential for their function. Over the years, specific Treg subsets have been […]

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Webinar: Single-cell multi-omics identifies unstable regulatory T-cell profiles

The Cytohub

Webinar by Prof. Susan Schlenner, University of Leuven, Belgium Regulatory T cells (Tregs) are a subset of CD4+ T cells that possess immunosuppressive functions.  They play a key role in human health as their malfunction results in allergies and auto-inflammatory disorders. Loss of regulatory T cells results in a rare autoimmune polyendocrine syndrome called IPEX, […]

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