Computational sorting with HyperFinder™

The Cytohub

In conventional flow cytometry sorting, hardware and instrument restrictions permit only one or two-dimensional regions to be used for gating. In addition, these gates can only be applied to measurements made during data collection. Once the data is collected, sophisticated machine learning algorithms present in software packages like FlowJo™ may be used to identify cell […]

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The new and improved anti-human CCR7 antibody

The Cytohub

The expression of CCR7 (CD197), a chemokine receptor that controls homing to secondary lymphoid organs, allows the differentiation of human memory T cells into functionally different subsets.1 CCR7+ memory cells express lymph-node homing receptors, efficiently stimulate dendritic cells and differentiate into CCR7- effector cells upon secondary stimulation. CCR7- memory cells express receptors for migration to […]

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CLL phenotyping with BD Rhapsody™ Targeted Panels and BD® AbSeq assays

The Cytohub

Chronic Lymphoid Leukemia (CLL), the most common form of leukemia in adults, is often characterised by progressive accumulation of incompetent lymphocytes in blood and bone marrow. Recent bulk RNA studies suggested that there are heterogeneities in CLL samples, prompting the need for single-cell RNA sequencing to study the underlying transcriptional profile. This presentation shows how […]

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BD single-cell multi-omics user meeting seminar series. Part 2 : Christina Chang, PhD

The Cytohub

Part 2: Evolution, challenges and the future of single-cell immunology – Christina Chang In this webinar, the second in the series of the BD Multi-Omics user day presentations, Christina Chang talks about how the BD single-cell, end-to-end workflow with informatics helps to increase the experimental power available to researchers. This workflow comprises of sample preparation, […]

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BD single-cell multi-omics user meeting seminar series. Part 1 : Dr Ricardo C. Ferreira, University of Oxford

The Cytohub

Simultaneous single-cell mRNA and epitope mapping of human CD4+ T-cells using the BD Rhapsody™ and the BD™ AbSeq platform  “ Currently a senior post-doctoral fellow in John Todd’s lab at the University of Oxford, my primary research aims at understanding how type 1 diabetes-associated genetic variants are functionally associated with disease. Through a combination of […]

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Breakthrough with the BD FACSMelody™ Cell Sorter

The Cytohub

Enable discoveries and get to your next breakthrough moment faster! The BD FACSMelody™ offers high-end sorting in an easy-to-use package for any researcher. It has been contributing to the research in cutting-edge areas like stem cell research, multiomics, immunology and cancer research. Here, we present a list of publications in high-impact journals, citing the BD FACSMelody™.  […]

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Creating the next generation of flow cytometry leaders -BD FACSMelody™ in action in Australia!

The Cytohub

“The FACSMelody™ is very simple to use. We can train a user within an hour, even if they  have limited flow cytometry experience”, says Dr. Andrea L. Holme, Senior Lecturer for Cytometry at the University of Western Australia, and a happy BD FACSMelody™ user. Watch the video to learn about the work being done by […]

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Flow cytometry in the study of anaerobic bacteria – The BIOASTER ANOXIC Platform

The Cytohub

The various species of bacteria inhabiting human and animal bodies, particularly in the gut microbiota, play key roles in many biological processes. Important health issues like undernutrition, irritable bowel syndrome,  metabolic disorders, skin diseases and many others are linked to gut bacteria and their functions. As bacteria in the gut are anaerobic and cannot be […]

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The role of immune checkpoint receptors in cancer immunity

The Cytohub

The human immune system fights not only external pathogens but also clears internal abnormalities like dying and cancer cells. The cancer immunity cycle begins when antigens produced by tumor cells are processed by dendritic cells for antigen presentation. This is followed by additional signals that activate and induce anti-tumor response by T cells, eventually resulting […]

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Origin of normal and neoplastic B-cells

The Cytohub

B-cell diversity is generated by a highly regulated, multistep process. Abnormal B-cell development and function can lead to malignant transformation. Advances in the understanding of the regulatory process that control B-cell lymphopoiesis and function have enabled proper classification of B-cell neoplasms and the development of targeted therapies. The attached poster enables you to get an […]

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BD Accuri™, the new generation personal flow cytometer, may be small but it is making waves in the world of science

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