CLL phenotyping with BD Rhapsody™ Targeted Panels and BD® AbSeq assays

Chronic Lymphoid Leukemia (CLL), the most common form of leukemia in adults, is often characterised by progressive accumulation of incompetent lymphocytes in blood and bone marrow. Recent bulk RNA studies suggested that there are heterogeneities in CLL samples, prompting the need for single-cell RNA sequencing to study the underlying transcriptional profile.

This presentation shows how the BD Rhapsody™ system can be used to simultaneously evaluate gene and protein expression. 32 proteins and ~500 genes were simultaneously analysed in single cells, revealing not only significant heterogeneity among CLL samples but also new cell types that were not previously associated with the disease.

Click here to download the presentation

BD, the BD Logo, BD Rhapsody are trademarks of Becton, Dickinson and Company © 2019 BD and its subsidiaries. All rights reserved.
For research use only. Not for use in diagnostic or therapeutic procedures.

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