Single-cell multimodal omics – Method of the Year 2019 by Nature Methods

BD Multi-Omics alliance BD Rhapsody BD Abseq

The journal Nature Methods has chosen single-cell multimodal omics as the Method of the Year 2019. This is a big acknowledgment of a new paradigm in cell biology research. Multimodal analysis enables the simultaneous measurement of multiple modalities or the integration of data from multiple experiments. For a long time now, the advantages of sequencing mRNA (scRNA – Seq) in individual cells, with a view towards understanding cellular heterogeneity and regulation, have been widely acknowledged. Non-destructive methods of cell analysis like flow cytometry have also evolved alongside, now enabling multi-parameter measurements of protein marker expression. Other methods like mass spectrometry and protein profiling have also helped gain insights into proteomics. The obvious next step is to integrate all the  ‘omics’ approaches by combining the data sets to get a holistic view of both gene and protein expression, enabling unparalleled insights into the actual biology of cells.

This new paradigm has been enabled largely due to advancements in technology and by developments in biochemistry and molecular biology. The recent years have seen great improvements in the sensitivity and robustness of these experimental approaches.

BD, through its flow cytometry, reagents and Multi-Omics portfolios, has long since been one of the forerunners in the development of this paradigm.

Read the editorial in Nature Methods.

 

BD and the BD Logo are trademarks of Becton, Dickinson and Company or its affiliates. © 2020 BD. All rights reserved.
Products are for Research Use Only. Not for use in diagnostic or therapeutic procedures.

Newsletter

Do not miss any essential information join us :)

Send me the Flowcytometry News newsletter. I expressly agree to receive the newsletter and know that I can easily unsubscribe at any time.

Diary

Stay up to date on what happens in Flowcytometry News !

Register and receive our newsletter each month

Send me the Flowcytometry News newsletter. I expressly agree to receive the newsletter and know that I can easily unsubscribe at any time.